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Olympique Lyon have also had a difficult spell in Ligue 1 recently, winning only one of their last five league games (two draws, two defeats), but in the Europa League, Les Gones are the team to beat. Paulo Fonseca’s side won all three games in the group stage without conceding a goal and are well on course for a top-eight finish.
Nevertheless, betting on another clean sheet for the south-eastern French side in Betis Sevilla vs. Lyon is too risky. After all, the Verdiblancos have lost only one of their last ten competitive games in the main rounds of UEFA competitions (four wins, five draws) – this year’s Conference League final against Chelsea (1-4).
It is interesting to note Olympique Lyon’s strong record in the Europa League against Spanish clubs. In six attempts, Les Gones have never lost a game against a La Liga representative (five wins, one draw). Against Beticos, OL not only remained unbeaten in two competitive games (one win, one draw), but also did not concede a goal. As we expect two stable defensive lines to neutralize each other to a certain extent in the Betis Sevilla vs. Lyon prediction, and we would prefer to refrain from the three-way system, we recommend betting on under 2.5 goals in this Spanish-French duel.
If you are looking for higher odds on Betis Sevilla vs. Lyon, you can also bet on a maximum of one team scoring. This fits in with the fact that “Les Gones” have won all three of their Europa League group stage matches without conceding a goal, as well as the stable defense of the Andalusians, who have also kept a clean sheet in two of their three international competitive matches this season.
Last but not least, there have never been goals on both sides in the only two competitive matches between the two clubs so far, which further rounds off this bet, which can be placed in the Bet-at-home app at odds of 2.25.
Betis Sevilla – Lyon Head-to-head comparison / H2H record
Head to head: 0 – 1 – 1
Two international competitive matches have taken place between the two teams so far, who clashed in the group stage of the Europa League in 2013/14. After the first leg in Andalusia ended in a goalless draw, Olympique Lyon recorded a 1–0 home win against Betis Sevilla in the second leg. The French side thus remained unbeaten in two games and without conceding a goal against the Verdiblancos.
Betis Sevilla – Lyon Tip
After the southeastern French side won their first three Europa League games of the 2025/26 season without conceding a goal, it is somewhat surprising that the betting odds for Betis Sevilla against Lyon are so clearly against “Les Gones.”
At LeoVegas, where new customers can claim a classic 100% bonus up to €100 with the LeoVegas bonus, odds of 3.95 are available for tip 2, which might even justify an outsider bet – if the Beticos weren’t so difficult to beat. The Andalusians have also not lost a Europa League game in the current league phase (one win, two draws), have played twice to nil and have only suffered one defeat in their last ten international competitive games (four wins, five draws).
This makes it very difficult overall to predict the outcome of this game between Betis Sevilla and Lyon, as there are valid arguments for both teams. Since both opponents pursue a defensive approach and their strength lies in avoiding goals, betting on under 2.5 goals is a very reasonable alternative to the three-way system.
