Does the underdog from Southampton stand a chance?
In the FA Cup quarterfinals, Southampton FC will face Arsenal FC on Saturday evening. The hosts are one of only two teams in this competition playing in lower-tier leagues, with Port Vale sitting one division below the Saints. Arsenal, on the other hand, is one of the six remaining Premier League clubs and naturally enters this matchup as the clear favorite. After losing the League Cup final to the Citizens, they’ll be looking to at least secure this cup competition.
The second-division side from Southampton already has a Premier League club on its record—in the last round of this cup, they won that matchup 1-0. Arsenal FC, on the other hand, narrowly defeated the third-division side from Mansfield Town 2-1.
Southampton has been very strong at home, at least in the domestic league, losing only three of their 19 home games this season. They also secured a cup victory in the fourth round of the FA Cup against Leicester City after extra time. Overall, the Saints have conceded 15 goals in 20 home games—with 14 in the league, they boast the joint-best home defense in the Championship. In none of these 20 competitive matches have the hosts conceded more than two goals, which is why our Southampton vs. Arsenal tip is for under 2.5 goals by the visitors.
In addition, the Saints are extremely prolific both at home and on the road. In their last 29 competitive matches, they have failed to score only twice—they have found the net in each of their last 16 matches—as well as in their last eight home games. In their last 14 home matches, they have also averaged 1.9 goals per game.
The Gunners remain in strong form and have lost only one of their last 15 competitive matches—though that was the most recent one, a 0-2 defeat to Manchester City in the EFL Cup final. In the FA Cup, they secured three wins against lower-division opponents—but in both away matches, Arsenal conceded exactly one goal, which supports our prediction of a goal from the hosts.
The 2-1 win in Mansfield marked one of the two highest-scoring games of the last seven matches. In fact, none of Arteta’s side’s last seven competitive matches have seen more than three goals scored. We are therefore betting on the Southampton vs. Arsenal odds for under 3.5 goals in the match.
Southampton – Arsenal Head-to-Head Comparison / H2H Record
In the head-to-head comparison between Southampton and Arsenal, the Londoners hold a clear advantage. In a total of 99 competitive matches—including 94 Premier League games and five encounters in domestic cup competitions—Arsenal have recorded 49 wins, while Southampton have celebrated only 23 victories. 27 matches ended in a draw. The goal difference also underscores the clear division of roles: Arsenal has scored 167 goals, while Southampton has scored 106.

Southampton – Arsenal Prediction
For the match between Southampton and Arsenal, the betting odds from the top bookmakers clearly favor the visitors from London. Arsenal FC has lost only one of its last 15 competitive matches—and in their last 23 away games, the Gunners have suffered just a single defeat. Recently, however, their competitive matches have been rather low-scoring – in their last seven competitive matches, there have never been more than three goals – and in five of those, the total was two or fewer.
Southampton, on the other hand, relies on its home strength and boasts the joint-best home defense in the Championship. They’ve also been prolific in front of goal – they’ve scored in each of their last 16 matches.

